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Multidrug resistance gene inhibits KCNH2. 1 / 1

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"In additional experiments, we also show that hERG blockade in HEK 293 cells was modulated by coexpression of efflux [breast cancer resistance protein (BCRP), multidrug resistance gene (MDR1)] and influx [organic anion transporting polypeptide (OATP) 2B1] transporters involved in the disposition and cardiac distribution of the drug."

22081364

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Multidrug resistance gene inhibits KCNH2. 1 / 1

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