IndraLab

Statements

Ubiquitinated BRAF is inactive. 1 / 1

1 |

"We showed that RNF149 bound directly to the C-terminal kinase-containing domain of wild-type BRAF and induced ubiquitination, followed by proteasome-dependent degradation, of the latter protein. Functionally, RNF149 attenuated the increase in cell growth induced by wild-type BRAF."

22628551

INDRA sources:

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IndraLab

Statements

Ubiquitinated BRAF is inactive. 1 / 1

INDRA sources:

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