IndraLab

Statements

Hemin inhibits NLRP3. 5 / 5
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"Moreover, hemin reduced malondialdehyde and reactive oxygen species production, and inhibited NF-kappaB and NLRP3 inflammasome activity."
24583148
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"Our study suggests that hemin inhibited NLRP3 inflammasome activation involved HO-1, reducing IL-1beta and IL-18 secretion and limiting the inflammatory response."
24583148
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"Likewise, in a sepsis induced ALI and ARDS murine model it has been shown that hemin inhibits NLRP3 inflammasome activation through the action of HO-1."
29868517
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"Supporting this hypothesis, a recent study showed that hemin inhibits NLRP3 inflammasome activation in a model of lung injury, through HO-1 activation [XREF_BIBR]."
29359167
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"In immunoprecipitation studies, hemin attenuated the interaction of NLRP3 with ASC and caspase-1."
23994575