IndraLab

Statements

ATXN3 activates Proteasome. 2 / 4

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"Increased ATXN3 prolongs the half-life of KLF4 by inhibiting KLF4 proteasome-associated degradation."

31563563

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reach

"Whether CHIP is the primary mediator of ubiquitin dependent degradation of ataxin-3 is controversial : XREF_BIBR reported that CHIP ubiquitinates ataxin-3 and directs it to the proteasome for degradation, whereas XREF_BIBR reported that another ubiquitin ligase, E4B, mediates ataxin-3 degradation while CHIP has no effect."

19084066

INDRA sources:

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IndraLab

Statements

ATXN3 activates Proteasome. 2 / 4

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