IndraLab

Statements

ATXN3 activates Proteasome. 1 / 3

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"Whether CHIP is the primary mediator of ubiquitin dependent degradation of ataxin-3 is controversial : XREF_BIBR reported that CHIP ubiquitinates ataxin-3 and directs it to the proteasome for degradation, whereas XREF_BIBR reported that another ubiquitin ligase, E4B, mediates ataxin-3 degradation while CHIP has no effect."

19084066

INDRA sources:

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IndraLab

Statements

ATXN3 activates Proteasome. 1 / 3

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