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Methotrexate decreases the amount of TNFAIP3. 1 / 2

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"Among them, methotrexate was shown to increase the expression of the NF-kB suppressor A20 (TNFAIP3) in human monocyte-derived GM-CSF polarized macrophages, leading to a significant repression of pro-inflammatory cytokines [33]."

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Methotrexate decreases the amount of TNFAIP3. 1 / 2

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