IndraLab

Statements

USP14 activates Stomach Neoplasms. 7 / 7
| 7
reach
"In one study, USP14 was found to promote GC cell proliferation, invasion, and migration by stabilizing the EMT protein vimentin."
36497313
reach
"YTHDF1 could promote the translation of USP14 protein, which then promoted the tumorigenesis and metastasis of GC (109, 137)."
36561529
reach
"Furthermore, an experiment using the USP14 inhibitor IU1 revealed that the inhibition of USP14 activity suppressed 5-fluorouracil (5-FU) resistance in GC cells."
37401238
reach
"Knockdown of YTHDF1 suppressed cell growth and colony formation, while overexpression of USP14 could rescue sh-YTHDF1 expressing GC cells from these effects (XREF_SUPPLEMENTARY)."
33791305
reach
"Taken together, these results suggest that USP14 accelerates the malignant behavior of GC cells."
27448976
reach
"Recently, researches have revealed USP14 enhances cisplatin resistance through affecting Akt and ERK signaling pathways and accelerates cell proliferation and migration in GC."
33791305
reach
"USP14 levels are elevated in GC and may be an independent disease-free survival marker in patients [38,39]."
36497313