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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

MYSM1 inhibits cell quiescence. 2 / 2

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"33 Using Ki67 as a marker of non quiescent cells, we show that Mysm1 -/- HSC loss of quiescence is rescued in Mysm1 -/- p53 -/- HSCs (XREF_FIG, right)."

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"Overall, this suggests that continued dysregulation of p53 effector functions beyond the upregulation of Bbc3 and PUMA contributes to persistent Mysm1 -/- HSC loss of quiescence, and also to the lymphoid differentiation arrest of Mysm1 -/- Puma -/- MPP4s."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...