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HDAC increases the amount of USP28. 2 / 2

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"Additional mechanism suggests that histone deacetylases 5 (HDAC5) promotes stability of USP28, thus enhancing stability of LSD1.Overexpression of USP28, HDAC5, and LSD1 is positively correlated in breast tumors."

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"16 Similarly, decreased HDAC activity promotes the acetylation of Htt protein and also causes an increase in Ube2e3, SUMo2, and USp28 expression."

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IndraLab

Statements

HDAC increases the amount of USP28. 2 / 2

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