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Statements


USP22 inhibits NLRP3. 5 / 5
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"In NLRP3 inflammasome-related diseases, USP22 inhibits NLRP3 inflammatory bodies through Atg5-dependent autophagy to degrade NLRP3 [23]."

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"USP22 in macrophages promotes LRR and PYD structural domain protein 3 (NLRP3) degradation and attenuates inflammation through autophagy-associated 5 homolog (ATG5)-mediated autophagy ."

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"Here, we demonstrated that USP22 (ubiquitin specific peptidase 22) promotes NLRP3 degradation and inhibits NLRP3 inflammasome activation."

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"Here , we demonstrated that USP22 ( ubiquitin specific peptidase 22 ) promotes NLRP3 degradation and inhibits NLRP3 inflammasome activation ."

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"USP22 suppresses the NLRP3 inflammasome by degrading NLRP3 via ATG5-dependent autophagy."