IndraLab

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UCHL5 inhibits HMBS. 1 / 1
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"Most importantly, it was shown that loss of uchl5, the human orthologue of ubh-4, also increases UPS activity and the degradation of proteotoxic proteins in mammalian cells XREF_BIBR, thus further verifying the value of C. elegans as a model organism to evaluate the consequences of UPS modulation."