IndraLab

Statements

USP9X inhibits Cell Survival. 4 / 4
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"A recent finding suggested that loss of USP9X, a deubiquitinase and activator of JAK-STAT signalling, in cytokine-receptor like factor 2-positive (CRLF pos ) ALL might contribute to cell survival by l[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"The data showed that FAM E3 decreased viral replication up to 86% whilst retaining cell viability above 90% (Fig. 2C)."
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"As inhibition of USP9X resulted in caspase 3 and caspase 8 activation and increased the rates of apoptosis, USP9X might promote cell survival by inhibiting apoptosis in glioma cells."
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"FAm significantly decreased cell viability and increased intracellular lipid accumulation, whereas LF significantly recovered cell viability without affecting lipid accumulation."
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