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SOX9 decreases the amount of USP22. 2 / 2
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"The upregulation of Sox9 induced mRNA expression of USP22 in CRC cells, whereas Sox9 knockdown led to significantly decreased USP22 expression compared to the control cells ( Fig. 5 A )."
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"Consistently, the protein level of USP22 in cells overexpressing Sox9 was markedly elevated compared to the control group, while the downregulation of Sox9 effectively inhibited the expression of USP2[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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