
IndraLab
Statements
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"Previous studies have described an interaction between Popeye domain‐containing proteins (Popdc1 and Popdc2) and TREK‐1 that is important for its regulation by protein kinase A, with implications for pacemaking in the mouse. xref Similarly, even earlier work identified an association between TREK‐1 and A kinase anchor protein 150 that controls response of channel to Gs‐coupled receptor activation. xref Our new findings together with our previous work xref indicate that β IV ‐spectrin associates with TREK‐1 and is essential for its proper membrane targeting in myocytes throughout the heart."