IndraLab

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ENPP2 activates SCN5A. 1 / 1
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"XREF_FIG shows that in ND7/23 cells, application of the sodium channel opener ATX-II augments Nav1.5-mediated sodium current but that this augmented current is not highly sensitive to A-803467 : ATX augmented SCN5A mediated late current was no more sensitive to A-803467 than was peak current (50% block at ~ 5000 nM)."