IndraLab

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MiRNA-1 decreases the amount of HCN4. 2 / 2
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"Furthermore, miRNA-1 suppression with antagomir-1 increased HCN2 and HCN4 protein levels; however, HCN2 and HCN4 mRNA levels were not affected, indicating that spironolactone stimulates miRNA-1 expression in the rat ischemic left ventricular myocardium after MI and that the upregulation of miRNA-1 expression partly contributes to the posttranscriptional repression of HCN protein expression."
26065643
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"MiRNA-1 suppression with antagomir-1 increased HCN2 and HCN4 protein levels; however, HCN2 and HCN4 mRNA levels were not affected."
26065643