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SH2B2 activates KCNH2. 2 / 2
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"The use in vitro of the action potential (AP) voltage clamp technique showed that the impaired inactivation of N588K hERG channels altered significantly the profile of I hERG during the plateau and repolarisation phases of ventricular APs, leading to increased I hERG occurring much earlier during the ventricular AP waveform XREF_BIBR, XREF_BIBR, XREF_BIBR."
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"Nonetheless, this exercise showed that I KCNQ or I hERG, could contribute to the development of long duration burstings APs in uterine cells."
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