IndraLab

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USP15 increases the amount of MMP9. 2 / 2
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"Consistently, USP15 shRNA impaired the protein levels of MMP9, N-cadherin, and Vimentin, but recovered E-cadherin expression in GINS1-overexpressing A172 cells, while the USP15 plasmid restored the protein levels of MMP9, N-cadherin, and Vimentin, but attenuated E-cadherin expression in GINS1-silenced U251 cells (Figure 6Q)."
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"Biochemical analysis revealed that USP15 knockdown inhibited matrix metalloproteinase (MMP)3 and MMP9 expression."
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