Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP9X activates SMURF1. 2 / 3

| 1 1

➶

reach

"USP9X can also modulate ubiquitin ligase SMURF1, a negative regulator of TGFbeta and BMP signaling that controls tumor cell migration and invasion by targeting Rho family proteins [XREF_BIBR]-[XREF_BIBR]."

25606592

➶

eidos

"In these cells , Ubiquitin Specific Peptidase 9 X-Linked ( USP9X ) stabilizes endogenous SMURF1 , and depletion of USP9X leads to down-regulation of SMURF1 and significantly impaired cellular migration ( Figure 7 ) ( 115 ) ."

30619734

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...