IndraLab

Statements


TLR inhibits CYLD. 1 / 1
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reach
"TLR signaling normally prevents caspase-8-, FADD- and RIPK3 dependent cell death pathways both through transcriptional upregulation of pro survival genes and through post-translational modification of key signaling proteins such as RIPK1 [XREF_BIBR], as well as inducing caspase-8-dependent cleavage of the pro necroptotic molecule CYLD [XREF_BIBR]."