IndraLab

Statements

SRSF1 binds USP39. 3 / 3
| 3
reach
"The interaction between USP39 and SRPK1/SRSF1 was analyzed by Western blot using anti-Flag tag (Abcam) or anti-SRSF1 (Abcam)."
34544400
reach
"This potentially originating from the iUSP domain cannot bind ubiquitin either, and the ZnF of USP39 could interact with the splicing independent on ubiquitin [64], which provides the opportunity for SRSF1 binding to USP39 , though further exploration is required to confirm the conclusion.Firstly, one remaining limitation is how USP39 drives the changes in VEGF-A , which needs further research to elucidate the specific mechanisms."
34544400
reach
"The same binding site was found in the interaction between USP39 and SRSF1 (Fig. 5E)."
34544400