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USP10 inhibits SQSTM1. 4 / 4
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"For instance, USP10 may stimulate p62 kinase or inhibit p62-phosphatase."

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"Furthermore, the promotion impact of USP10 on autophagy response was demonstrated In HLF, as indicated by increased levels of LC3II/LC3I and decreased p62 (Fig. S1E)."

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"Finally, we found that carriers of the USP10 genotype had decreased synthesis of p62 and LC3-II compared to non-carriers (p = 0.005 and p = 0.047; Figure 3B,C)."

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"These results indicated that USP10 and p62 cooperatively inhibit MG-132-induced cell death by promoting the formation of aggresomes and p62 aggregates."