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Statements

Hydroxychloroquine inhibits azithromycin. 4 / 4
| 3 1
eidos
"In a small study , hydroxychloroquine significantly decreased viral load in COVID-19 patients and the addition of azithromycin further enhanced the reduction in viral load ."
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eidos
"In a small study , hydroxychloroquine significantly decreased the viral load in COVID-19 patients and the addition of azithromycin further enhanced the reduction in viral load [ 10 ] ."
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eidos
"of viral RNA copies / millilitre of blood ) Comment to primary outcome : Because the biological plausibility of this trial is in the possibility that hydroxychloroquine inhibits virus replication and azithromycin potentially enhances this , the primary outcome was chosen to prove or disprove that decrease virus replication reduces the damage to the lungs and hence less patients die or progress into frank acquired respiratory distress syndrome ( ARDS ) with the need of protracted mechanical ventilation and often resulting in delayed death or failed functional outcomes [ 10 ] ."
| PMC
reach
"By de-acidifying acidic organelles, CQ and HCQ could prevent the accumulation of azithromycin in acidic organelles and increase its concentrations in cytosol where azithromycin exerts inhibitory effects on viral replication [130] ."
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