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MYSM1 activates Interferon. 2 / 2
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"Similarly, upon infection with L. monocytogenes, Mysm1 −/− mice elicited a more robust pro-inflammatory and type I IFN gene activation in multiple organs including the peritoneum ( Figure S7 B) and sp[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Interestingly, type I IFN, pro-inflammatory cytokines, TBK1, and IRF3 induced by DNA sensing were downregulated by MYSM1, upregulated by sh- Mysm1 , and enhanced in Mysm1 −/− mice."
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