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USP38 inhibits Genomic Instability. 2 / 2

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"USP38 is expressed at low levels in ccRCC, and USP38-deficient mice have increased genomic instability, indicating that USP38 is a regulator of the DNA damage response [19]."

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"It has been shown that USP38 affects DNA damage repair by regulating the activity of HDAC1 , meanwhile , a low expression of USP38 causes genome instability , which may lead to tumorigenesis [ 18 ] ."

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USP38 inhibits Genomic Instability. 2 / 2

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