IndraLab

Statements

USP37 increases the amount of NFE2L2. 3 / 3
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"Herein, the wild-type USP37, but not the enzymatically inactive mutant USP37-C350S, increased NRF2 protein levels (Fig. 2a)."
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"Furthermore, USP37 expression raised endogenous NRF2 protein levels without affecting NRF2 RNA expression (Fig. 1c, d)."
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"We discovered that the expression of one particular DUB, USP37, significantly upregulated the NRF2 protein level (Fig. 1b)."
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