IndraLab

Statements

KCNMA1 activates 3-methylcholanthrene. 3 / 3
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"MaxiPost (BMS-204352), a BK channel opener, was found to initiate migraine attacks, increase MCA velocity, and dilate superficial temporal arteries and radial arteries [62]."
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"This LCA action is significantly larger than LCA induced BK channel activation in ACA, MCA, PCA and MA myocytes (p < 0.05)."
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"Collectively, data from our studies documenting BK channel-mediated MCA constriction at sub-μM to μM levels of PREG strongly suggest that the aforementioned treatments with PREG could pose potential associated risks, due to PREG-induced cerebral artery constriction."
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