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USP9X activates localization. 4 / 4
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"Thus, our data indicate that USP9X promotes DVL2 localization to puncta that also contain AP-2 (Figure S5A), while loss of USP9X activity results in WWP1-dependent re-distribution of DVL2 to actin-rich projections in MDA-MB-231 breast cancer cells.One feature of WNT5a-mediated PCP activation is Rho activation, which is DVL2 dependent and required for induction of cell migration by the WNT-PCP pathway (Zhu et al., 2012)."
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"Depletion of USP9X induced down-regulation and mis localization of NPHP5 (XREF_FIG and XREF_SUPPLEMENTARY, XREF_SUPPLEMENTARY, XREF_SUPPLEMENTARY Figs)."
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"The fluorescent tag FAM enabled the cellular uptake and the intracellular localization of Chol-siRNA to be monitored."
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"In no case did the other investigations demonstrate that FAM had caused incorrect localization of a lesion.For each of the 11 patients detailed in Table 1 , the referring clinician was asked whether t[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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