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Antioxidant inhibits NLRP3. 7 / 7
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"In combination, corilagin inhibits the ROS/TXNIP/NLRP3 pathway to suppress inflammasome activation and pyroptosis, indicating its potential as an antioxidant in reducing GA dependent on NLRP3."
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"On the one hand, Nrf2 can reduce ROS production by inducing the expression of antioxidant‐related genes, thereby inhibiting NLRP3 activation."
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"Antioxidants are shown to reverse NLRP3 activation ( 188 ) ."
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"The aim of this study is to explore whether Nrf2 antioxidant pathway negatively regulates the ChTLR15/NLRP3 inflammatory pathway stimulated by Eimeria tenella infection."
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"Indeed, preliminary studies suggest that antioxidants inhibit NLRP3 priming rather than NLRP3 activation [ xref ]."
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"Pterostilbene, the substantial antioxidant in blueberries, remarkably reduced NLRP3 inflammasome, NF-κB expression, cardiac oxidative stress and inflammation via activating AMPK/Nrf2/heme oxygenase (H[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In the same study it was demonstrated that MB downregulates ROS , NFB , and NLRP3 by the antioxidant effect which reduces NFkB and NLRP3 proteins expression by ROS / NF-KB-NLRP3 pathway ."
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