IndraLab

Statements

USP15 leads to the dephosphorylation of IRF3. 2 / 2
| 2
reach
"To further confirm the results, SEV induced phosphorylation of NF-kappaB subunit p65 and IRF3 were enhanced by the knockdown of USP15 (XREF_FIG)."
26061460
reach
"Moreover, knockdown of USP15 increased the levels of K63-lined ubiquitinated RIG-I (Fig. 7D, lane 1 and lane 3) and phosphorylated IRF-3 (Fig. 8E, lane 1 and lane 3), whereas miR-26a induced K63-RIG-I and phosphorylated IRF-3 was largely abrogated in the setting of USP15 knockdown (Fig. 7D and E, lane 3 and lane 4)."
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