IndraLab

Statements

CACNA1A activates CFI. 5 / 5
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"Expression of PEX5R C terminally fused to GFP ( GFP PEX5R), however, completely prevented the isoprenaline-induced shift in voltage dependent activation of I f in these cells (ΔV 1/2 by isoprenaline[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
19555650
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"As shown in Figure 8 A, the β-adrenergic agonist isoprenaline shifted voltage dependent activation of I f in mock-infected embryonic atrial cardiomyocytes expressing green fluorescent protein (GFP) [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
19555650
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"Though this is relatively smaller as compared to the ISO-induced shift (about +7 to +18 mV) of the I f activation curve in murine SAN cells (Alig et al., xref ; Baruscotti et al., xref ; Liao et al., xref ), it is close to observed values of 8.8 mV (Accili et al., xref ) and 5.3 mV (Accili et al., xref ) for a 1 μM ISO-induced shift in voltage-dependent activation of I f in adult rabbit SAN cells."
23060799
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"cAMP potentiates voltage-dependent activation of I f either by binding directly to HCN4 channels ( xref ; xref ) or by protein kinase A (PKA)–mediated phosphorylation of HCN4 channels ( xref )."
28057842
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"If the ratio of HCN2 over HCN4 transcript is also a contributing factor to the voltage-dependent activation of I f , an altered ratio of HCN2 over HCN4 should change I f ."
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