IndraLab

Statements


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sparser
"Immunostaining of Drosophila S2 cells ( xref E–P) and imaginal discs ( xref Q,R,) further revealed that the transgenic wild-type Prp8 (Prp8 wt ) as well as the RP-Prp8 mutant variants primarily localized to the cytoplasm where the endogenous Drosophila Prp8 or transgenic human Flag::PRPF8 proteins were also mostly confined."

sparser
"Interestingly, when RUVBL1–RUVBL2, AAR2, ECD, RPAP3-PIH1D1 and ZNHIT2ΔC were added to the Flag-affinity resin loaded with Flag-PRPF8, all these proteins eluted with PRPF8 (Figure xref , xref )."

sparser
"However, when Flag-PRPF8 was present in the lysates, RUVBL1–RUVBL2 formed a direct complex with PRPF8, and this interaction was still detected when ATP was added to the reaction (Figure xref )."