IndraLab

Statements


USP21 activates BMP. 2 / 2
| 2

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"RNA-seq reveals enriched BMP signaling in Tg-SwDI mice that is rescued by Usp16 haploinsufficiency."

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"For the first time, we show that targeting USP16 in a mouse model of AD rescues two aberrant aging pathways, Cdkn2a and BMP, which can restore self-renewal of NPCs, decrease astrogliosis, and retard cognitive decline (Figure 1)."