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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

STAT3 increases the amount of USP25. 3 / 3

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"9 At the transcriptional level, the expression of USP21 in mESCs was activated by the LIF and STAT3 pathway, which was critical for the maintenance of mESC and the self-renewal of mESCs."

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"At the transcriptional level, the expression of USP21 in mESCs was activated by the LIF and STAT3 pathway, which was critical for the maintenance of mESC and the self-renewal of mESCs."

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"In accordance with these results, treatment with Cryptotanshinone, a specific inhibitor of STAT3 by inhibiting STAT3 Y705 phosphorylation, reduced the expression of USP21 (XREF_SUPPLEMENTARY)."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

STAT3 increases the amount of USP25. 3 / 3

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