IndraLab

Statements


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"Clearly, it will be very interesting to characterize the interaction between fibronectin and GPIIb/GPIIIa in the immature and mature blood cell types and to determine further the downstream signaling [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"In addition, FN1-CD61 expression under the control of c-Rel activation highlights a positive feedback loop."

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"ITGB3, an integrin that binds to fibronectin, vitronectin, and collagen, facilitates interactions between the cell cytoskeleton and the extracellular matrix [65]."
| PMC

sparser
"Disruption of fibronectin-integrin (FN1-ITGB3) signaling contributed to epithelial-extracellular matrix separation, facilitating erosion formation."

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"Integrin beta-3 (ITB3) can interact with fibronectin (FN), which is abundant in the myocardium matrix 11."

sparser
"High levels of FN1 interact with integrin ITGB3, regulating gene activity that affects various signaling pathways and is involved in ovarian follicle development, maturation, ovulation, and corpus luteum formation xref ."

sparser
"Although integrin αIIbβ3 can also bind to fibronectin, we did not observe an inhibition of LEC adhesion to fibronectin when integrin αIIbβ3 was blocked."

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"As integrin beta-3 also binds to fibronectin, out study provides further evidence that integrin-fibronectin interaction is essential to stem cell mediated repair."

sparser
"Particularly at high shear stress, stable platelet adhesion is achieved by other integrin ligands with their corresponding ligands such as integrin αIIbβ3 bound to fibronectin and fibrinogen/fibrin, α[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

No evidence text available

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"We treated cells with antibodies to either integrin beta 1 to block collagen-I binding integrins (which all include the beta 1 subunit), or integrin beta 3 that binds fibronectin and other RGD contain[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"On the one hand, with a shear rate below 1000 s − 1 , aggregation is primarily due to the αIIbβ3-fibronectin interaction; on the other hand, with a shear rate above 10,000 s − 1 , aggregation is regulated by the GPIbα-vWF interaction, even in the absence of platelet activation by αIIbβ3 [ xref , xref , xref ]."

sparser
"For example, platelet membrane receptor-like GPIb-IX-V binds with vWF, and integrin α2β1, GPVI, and GPIV bind with collagen in addition to integrin α5β1 and αIIbβ3 , which bind with fibronectin of the[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"