IndraLab

Statements

NFE2L2 activates KCNMA1. 4 / 4
| 4
reach
"First, genetic knockout of Nrf2 profoundly diminished BK channel activity in the coronary arterial SMCs of mice, and this was accompanied by remarkable reductions in BK-alpha and BK-beta1 expression, as well as the BK-alpha and BK-beta 1 ratio."
32147517
reach
"These results indicate that expression of BK-beta1 is closely regulated by Nrf2 and vascular BK channel function can be restored by Nrf2 activation."
28429615
reach
"Adenoviral expression and pharmacological activation of Nrf2 increased BK-alpha and BK-beta1 protein levels and enhanced BK channel activity in coronary arterial SMCs."
32147517
reach
"Role of Nrf2 Signaling in the Regulation of Vascular BK Channel beta1 Subunit Expression and BK Channel Function in High-Fat Diet Induced Diabetic Mice."
28465407