IndraLab

Statements

USP12 activates Angiotensin-2. 3 / 3
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"Lu et al. revealed that USP12 promoted Ang II-induced cardiomyocyte hypertrophy; METTL3 expression was induced by Ang II but was downregulated in USP12 knockdown neonatal rat cardiomyocytes (NRCMs)."
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"We found that USP12 promoted Ang II-induced cardiomyocyte hypertrophy, and USP12 deficiency attenuated cardiac hypertrophy in mice."
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"Our study demonstrated that USP12 promoted Ang II-induced cardiac hypertrophy via regulating METTL3 expression."
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