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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CUL1 activates ATXN3. 1 / 1

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"Knockdown of CUL1 abolished FBXL3 mediated reduction of normal ATXN3, but only accounted for about half of the observed FBXL3 facilitated decrease of pathogenic ATXN3 (XREF_FIG), suggesting that FBXL3 handles or recognizes normal and mutant ATXN3 differently."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...