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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

EIF3F inhibits AKT. 3 / 5

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"EIF3f overexpression activates p53 and Bax and inhibits Akt and ERK signaling."

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"Furthermore, eIF3f can suppress Akt and ERK signaling, as well as stabilize p53 [60] In our data, eIF3f was also down-regulated, as is the case in melanoma and pancreatic cancer."

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"Targeting eIF3f Suppresses the Growth of Prostate Cancer Cells by Inhibiting Akt Signaling."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

EIF3F inhibits AKT. 3 / 5

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