IndraLab

Statements

USP4 activates epithelial to mesenchymal transition. 10 / 10
| 1 9
reach
"9 , 10 For example, USP4 enhances the invasive and migratory capabilities of melanoma cells by facilitating EMT."
39135915
reach
"Collectively, these data demonstrated that USP4 promotes melanoma cell migration and invasion by promoting EMT."
29542252
reach
"Our study showed that after interfering with USP4 expression, lung adenocarcinoma cells changed from a long spindle shape to round, the migration and invasion abilities of cells decreased, N-cadherin expression decreased, and E-cadherin expression increased, indicating that USP4 promoted the invasion and migration of lung adenocarcinoma cells by promoting the EMT of cancer cells."
40169699
reach
"Moreover, USP4 is recently showed to enhance EMT and metastasis by stabilizing TbetaRI [XREF_BIBR]."
22981905
eidos
"Recently , USP4 was found to mediate deubiquitination of the epithelial-mesenchymal transition ( EMT ) transcriptional factor Twist1 to promote lung cancer cell stemness ( Li et al ., 2020 ) ."
33681193
reach
"3.4 USP4 up-regulation contributes to melanoma invasion and migration by promoting EMT."
29542252
reach
"For example, USP4 drives breast cancer cell invasion via Relaxin/TGF-β1/Smad2/MMP-9 (matrix metallopeptidase 9) signalling [93] and promotes hepatocellular carcinoma metastasis by enhancing TGF-β sign[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
34678225
reach
"USP15 enhances the tumorigenic effects of TGF-β in glioblastoma (80), while USP4 promotes TGF-β-induced EMT and cell migration in breast cancer."
35616129
reach
"LOXL3-promoted hepatocellular carcinoma progression via promotion of Snail1/USP4-mediated epithelial-mesenchymal transition."
35841383
reach
"USP4 promotes the migration and invasion of lung adenocarcinoma cells by regulating cellular EMT processes."
40169699