IndraLab

Statements

OTUD1 binds Ad. 7 / 7
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"Otud1-overexpressing mice and control mice were generated by injecting recombinant adenovirus Ad-Otud1 or Ad-GFP into WT mice, followed by hepatic I/R operation."
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"The recombinant adenovirus (Ad-Otud1) and the control adenovirus (Ad-GFP) were purchased from GeneChem (Shanghai, China)."
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"Ad-GFP (5 × 10 9  pfu) or Ad-Otud1 (5 × 10 9  pfu) were injected into C5 7BL /6J WT mice via the tail vein at a volume of 125 μL 36 h before hepatic I/R operation [ xref ]."
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"Figure xref Gdemonstrate that Ad-Otud1 increased the cell surface of NRCMs, while the cellular surface of cardiomyocytes was significantly reduced in the Ad-shOtud1 cell group (Figure xref H)."
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"Primary hepatocytes were isolated from Nrf2-WT and Nrf2-KO mice, which were injected with Ad-GFP or Ad-Otud1 via tail vein and subjected to H/R treatment."
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"To elucidate the regulatory mechanism of Otud1 in cardiac hypertrophy, RNA sequencing analyses of NRCMs infected with Ad-GFP and Ad-Otud1 were performed."
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"Then, Otud1-expressing adenovirus (Ad-Otud1) and shRNA targeting Otud1 (Ad-shOtud1) were constructed to infect NRCMs."
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