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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP1 activates CDKN1A. 2 / 2

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"Increased USP1 levels were also observed upon siRNA mediated p21 depletion (see XREF_FIG, lanes 5 and 6)."

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"Significantly, CDKN1A siRNAs restored S phase entry in USP1 deficient U2-OS cells, indicating that p21 is essential for the cell-cycle arrest induced by USP1 knockdown.If ID degradation in the absence[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...