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OTUD1 activates AHI1-mediated Tyk2. 1 / 1
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eidos
"Importantly , OTUD1 knockdown inhibited the AHI1-mediated upregulation of Tyk2 levels ( Fig. 4e ) , suggesting that OTUD1 is essential for the AHI1-mediated regulation of Tyk2 protein levels ."