IndraLab

Statements


STAMBP activates EV-Cx43. 2 / 2
| 2

eidos
"Here , depletion of AMSH decreased EV-Cx43 levels , suggesting that lysosomal degradation of Cx43 was promoted , whereas knockdown of USP8 up-regulated the release of ubiquitinated Cx43 in EVs ."

eidos
"Our results show that siRNA-mediated knockdown of USP8 increased EV-Cx43 release , as well as the total number of vesicles , whereas depletion of AMSH decreased EV-Cx43 levels ( Figs 4C and S5I ) ."