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USP26 activates DNA-templated transcription. 2 / 2

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"In LNCaP cells, Usp26 depletion by siRNA enhances AR dependent transcription, suggesting it acts on a factor that is negatively regulated by ubiquitination (Dirac and Bernards, 2010)."

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"USP26 has been reported to bind to AR through LXXLL and FXXFF motifs to enhance AR deubiquitination and enhance AR downstream transcription [20]."

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IndraLab

Statements

USP26 activates DNA-templated transcription. 2 / 2

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