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USP10 activates lactate. 2 / 2
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"Moreover, the transfection of USP10 shRNA also decreased the glucose uptake, ATP production and lactate production of PC cells (Fig. 3A–C)."
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"Expression of USP10 shRNA increased lipid droplet content, lactate production and glycolytic gene expression in control cells but not in AMPKalpha deficient cells (XREF_SUPPLEMENTARY), indicating that USP10 regulates cellular metabolism through AMPK."
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