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UCHL3 activates EP300. 2 / 2
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"The deubiquitinase UCHL3 mediates p300-dependent chemokine signaling in alveolar type II cells to promote pulmonary fibrosis."

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"As expected, overexpression of wild-type UCHL3 increased the half-life of p300 compared with that of the inactive mutant UCHL3 (Fig. 3h and Supplementary Fig. 13c)."