IndraLab

Statements

UCHL1 inhibits Melanin. 3 / 3
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"A melanin content assay revealed that overexpression of UCHL1 significantly inhibited melanin synthesis in NHEMs and MNT-1 cells by 16.2% and 35.5%, respectively."
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"Conversely, knockdown of UCHL1 using siRNA induced melanin contents by 21.5% in NHEMs."
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"In contrast, overexpression of UCHL1 in melanocytes via adenovirus transfection led to downregulation of tyrosinase, dopachrome tautomerase, and tyrosinase related protein-1 and decreased melanin contents."
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