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SSRI fluoxetine activates KCNK2. 1 / 1
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"Spadin was administered 30 min before the test by intracerebroventricular (i.c.v.), intravenous (i.v.), or intraperitoneal (i.p.) route at doses of 10 -4 to 10 -8 M. Its effects were compared to the behavior observed in kcnk2 -/- mice and in wild-type mice treated with the efficient SSRI fluoxetine (i.p., 3 mg/kg)."