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SIRT2 inhibits COPS6. 2 / 2
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"As shown in Fig. 3 F–H, knocking down the expression of SIRT2 exacerbated the Ang II-induced myocardial hypertrophy, more important, the inhibition of SIRT2 could reverse the decrease of cardiomyocyte[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"29 The latest research showed that constitutive photomorphogenic 9 signalosome complex subunit 6 (CSN6) and plant homeodomain finger protein 19 (PHF19) exacerbate the pathological myocardial hypertrophy induced by Ang II by inhibiting the expression of SIRT2, and the overexpression of SIRT2 can reduce the effect of CSN6 in promoting myocardial hypertrophy."
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