IndraLab

Statements

KCNMA1 increases the amount of calcium(2+). 2 / 2
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"History of seizures has been shown induce expression of more Ca 2+ sensitive BK channel splice variants, which may underlie the difference in paxilline efficacy between the two states."
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"Coexpression of beta4 in heterologous cells slows activation kinetics of BK channel currents XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR, generally increases the amount of Ca ++ and depolarization required for channel gating XREF_BIBR, XREF_BIBR, XREF_BIBR but see XREF_BIBR, and confers resistance to the specific peptide antagonists iberio- and charybdotoxin XREF_BIBR, XREF_BIBR."
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